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Tag Archives: Immune system

Skin bacteria regulate the immune response

25 Wednesday Sep 2013

Posted by sedeer in Bacteria, Disease, Mammals

≈ 8 Comments

Tags

Bacteria, biology, Complement system, Health, Immune system, microbes, microbiome, Mouse, Popular science, science

E. coli (Photo credit: Wikipedia)The skin is one of our body’s first lines of defense, but it’s also home to a rich community of microbes — the skin microbiome.  These bacteria are important in protecting us from pathogens; changes in the skin microbiome are linked with conditions ranging from dermatitis to psoriasis.  In a paper published this month in the journal PNAS, a team of scientists from the University of Pennsylvania showed that these bacteria don’t just live on our skin, but also play a role in regulating our immune response. Continue reading →

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Excessive hygiene lets the immune system run amok

29 Thursday Mar 2012

Posted by sedeer in Bacteria, Immunology, Microbiology

≈ 8 Comments

Tags

Allergy, animals, Asthma, biology, colitis, Health, Hygiene Hypothesis, Immune system, Mouse, Popular science

Since moving to Finland, I’ve become accustomed to asking guests whether they have any allergies before I prepare dinner.  I grew up in the developing world where allergies and asthma seem to be much less common than they are here; in fact, various studies have found higher rates of allergy and autoimmune conditions in developed than developing countries.  One explanation for this is the “hygiene hypothesis“, which proposes that excessive hygiene early in life can affect the development of the immune system and result in allergic conditions and autoimmune diseases in later life. In a recent study appearing in Science, a team of scientists in Germany and the United States present evidence supporting the hygiene hypothesis and the importance of an early challenge to the immune system.
Continue reading →

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