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Inspiring Science

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Category Archives: Humans

Gut bacteria and diabetes: the saga continues

26 Friday Oct 2012

Posted by sedeer in Bacteria, Genetics, Humans

≈ 4 Comments

Tags

Bacteria, biology, diabetes, Diabetes mellitus type 2, Gut flora, Health, metagenome, Metagenomics, Popular science, science, sequence

Low-temperature electron micrograph of a cluster of E. coli bacteria, magnified 10,000 times. Each individual bacterium is oblong shaped. (Photo credit: Wikipedia)Type 2 diabetes is a serious global epidemic, having grown from 30 million cases to nearly 300 million over the past three decades. Although several recent studies have shown a link between type 2 diabetes and our gut bacteria, we’re still only at the dawn of learning about the microbiome. There’s a great deal we don’t yet know, including what kinds of bacteria live in our gut and how they go about making a living there. In a paper published in the September issue of Nature, a team of scientists from China and Denmark used whole genome sequencing technologies to overcome these gaps in our knowledge and get some more clues about the relationship between our gut bacteria and this disease. Continue reading →

Blond Melanesians: what else are we missing?

05 Friday Oct 2012

Posted by sedeer in Evolution, Genetics, Humans

≈ 5 Comments

Tags

biology, Blond, diversity, Europeans, Genetics, Genome, Melanesians, Popular science, science, science and society, Science in Society, Solomon Islands

English: Blond Vanuatu boyOn the Solomon Islands in the south-eastern Pacific, it’s not uncommon to come across Melanesian children with dark skin and remarkably blond hair. While most people might take this unusual trait as a sign of European ancestry, Sean Myles wasn’t convinced. Curious to understand how the darkest skinned people outside of Africa could also have the highest frequency of blond hair outside of Europe, he led a team of scientists to unravel the genetics behind this mystery. The striking results of their research should serve as a note of caution about what we’re learning from the rapidly growing field from human genomics.
Continue reading →

We’ve been wrong about when humans spread out from Africa

14 Friday Sep 2012

Posted by sedeer in Evolution, Genetics, Humans

≈ 7 Comments

Tags

Hominidae, Human, Mitochondrial DNA, Mitochondrial Eve, Mutation rate, Popular science, Radiocarbon dating, science

mtDNA map of human migrations (Wikipedia)Most of the interesting recent events in human evolution probably happened longer ago than we had thought, according to Aylwyn Scally and Richard Durbin of the Sanger Institute.  In an opinion piece published in Nature Review Genetics this week,  they re-examine the story of how humans left Africa, taking into account new data from several recent whole-genome studies.

Continue reading →

Debating our ancestors’ sex life

05 Wednesday Sep 2012

Posted by sedeer in Evolution, Humans

≈ 9 Comments

Tags

biology, Denisova hominin, Denisovan, DNA, Evolutionary Anthropology, Genome, Homo floresiensis, Human, Neandertal, Neanderthal, Popular science, science

Neanderthal; Photo credit: hairymuseummattAround 60,000 years ago, modern humans left Africa, the cradle of our species. As we spread across the face of the Earth, we discovered that we weren’t the first or the only humans to make that sojourn.  From Central Asia to Europe, we met our distant cousins the Neanderthals, descendants of a 500,000 year old migration; further east were the Denisovans, ranging from Sibera to Southeast Asia.  Although these other humans died out around 30,000 years ago, some comfort can be found in the knowledge that a part of them lives on in us.  Genetic evidence uncovered in the past few years suggests that our migrating ancestors may have mated with these other humans during their encounters.  Not everyone was convinced, though, launching an ongoing debate about whether the genetic similarity might be due to common ancestry rather than inbreeding. Continue reading →

Promoting incompetence

10 Friday Aug 2012

Posted by sedeer in Humans, Modelling

≈ 5 Comments

Tags

competence, Hierarchy, organisation, organisational psychology, Peter Principle, Popular science, promotion, psychology, simulation, Work

From Dilbert’s PHB to The Office, the incompetent manager is such a popular trope that it’s in danger of becoming a tired cliché. Is this just a sign of the times or might it reflect some deeper truth? Could this be because of how we decide who to promote? A recent study has confirmed a counter-intuitive idea proposed over 30 years ago — that promoting those who perform best may, in fact, be a losing strategy.
Continue reading →

Through the gut: how plants in food regulate genes in animals

27 Sunday May 2012

Posted by sedeer in Genetics, Humans, Mammals, Plants

≈ 4 Comments

Tags

biology, digestion, DNA, Gene expression, GMO, Health, horizontal transfer, Human, MicroRNA, Mouse, nutrition, Popular science, RNA, science

In an exciting discovery reported last year, a team of Chinese researchers found that some of the genetic material in our food might survive digestion and go on to regulate our genes and affect our physiology.  This new mechanism for genetic interactions between very different species raises interesting evolutionary questions and will probably have implications for the study of health and nutrition, but it’s important to understand what the study was actually about, particularly since this will likely affect the debate around GMO foods. Continue reading →

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